The FLiRT variants, including KP.3, are descendants of the JN.1 subvariant of Omicron. These variants were first detected through wastewater surveillance in the U.S. and have since been identified in other countries such as Canada and the UK.
KP.3, like other FLiRT variants, has specific mutations on its spike protein, which may enhance its ability to evade immunity from previous infections or vaccinations.
Vaccination remains a critical tool in combating COVID-19, including the KP.3 variant. While the KP.3 variant shows some resistance to antibodies generated by the current monovalent vaccines targeting the XBB.1.5 variant, vaccination still provides significant protection against severe illness and hospitalization.
To protect against KP.3 and other variants, it's essential to stay up to date with COVID-19 vaccinations. Additional preventive measures include wearing masks in crowded places, maintaining good hand hygiene, and ensuring proper ventilation in indoor spaces.